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 | Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
29/01/2020 |
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Actualizado : |
29/01/2020 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
REGUEIRO, M.; PÉREZ-CLARIGET, R.; GANZÁBAL, A.; ABA, M.; FORSBERG, M. |
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Afiliación : |
M. REGUEIRO, Department of Animal Production, Fac. Agric., Univ. Rep. Uruguay, A., Montevideo, Uruguay; Centre for Reproductive Biology, Dept. Clin. Chem., Fac. Vet. M., Uppsala, Sweden; R. PÉREZ CLARIGET, Department of Animal Production, Fac. Agric., Univ. Rep. Uruguay, A., Montevideo, Uruguay; Centre for Reproductive Biology, Dept. Clin. Chem., Fac. Vet. M., Uppsala, Sweden; ANDRES RICARDO GANZÁBAL PLANINICH, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; M. ABA, Department of Physiopathology, Fac. Vet. Sci., UNCPBA, Camp. Univ., Tandil, Argentina; Centre for Reproductive Biology, Dept. Clin. Chem., Fac. Vet. M., Uppsala, Sweden; M. FORSBERG, Centre for Reproductive Biology, Dept. Clin. Chem., Fac. Vet. M., Uppsala, Sweden. |
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Título : |
Effect of medroxyprogesterone acetate and eCG treatment on the reproductive performance of dairy goats. |
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Fecha de publicación : |
1999 |
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Fuente / Imprenta : |
Small Ruminant Research, August 1999, Volume 33, Issue 3, Pages 223-230. Doi: https://doi.org/10.1016/S0921-4488(99)00024-3 |
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ISSN : |
0921-4488 |
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DOI : |
10.1016/S0921-4488(99)00024-3 |
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Idioma : |
Inglés |
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Notas : |
Article history: Accepted 27 January 1999. |
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Contenido : |
ABSTRACT.
The incidence of short oestrous cycles and kidding rate in dairy goats were evaluated after administering a low dose (500 IU) of equine chorionic gonadotrophin (eCG) during two breeding seasons. The first year, 46 does (Saanen, n = 10; Nubian, n = 26; and their local crossbred, n = 10) were used. The second year of the study was performed on 34 of the same does (Saanen, n = 4; Nubian, n = 19; local crossbred, n = 11). The goats were synchronised with intravaginal sponges that contained medroxyprogesterone acetate during a period of 14 days. At the time of sponge withdrawal the animals were assigned to two groups: the eCG group was injected with 500 IU of eCG i.m. and the control group was injected with 2 ml of saline solution. Oestrous detection began 12 h after sponge removal. Once a doe was detected to be on heat, it was mated twice: at the moment of detected heat and 12 h later. The animals which presented short cycles were mated again according to the same schedule. To determine the progesterone concentration, all of the animals were bled on the day of standing heat and every second day over a period of 22 days during the second year. All of the does exhibited oestrus within 4 days after sponge removal. The average time (mean ± SD) between sponge withdrawal and standing heat was significantly shorter in the eCG group than in the control group (34.5 h ± 11.9 versus 42.9 h ± 19.6). More animals in the eCG group returned to oestrus than those in the control group (62.5% versus 15%; p < 0.0001). In the eCG group 77.5% Nubian, 63.6% crossbreed and 14.3% Saanen does returned to oestrus while the corresponding percentages for the control group were 8.7, 10 and 42.9%, respectively. Seventy-six percent (n = 19) of the animals which returned to oestrus in the eCG group did so after a short oestrous cycle, while the corresponding figure in the control group was 16.7% (n = 1) (p = 0.0051). Mean progesterone levels in the mid luteal phase of pregnant and non-pregnant eCG treated animals, were higher than the levels found in the control group. Kidding rates differed significantly between eCG-treated (41.0%) and control animals (64.1%) (p < 0.05), but no significant difference was observed in the mean number of live kids born per doe. Animals weighing less had a higher incidence of short oestrous cycles and a lower kidding rate than heavier animals. In conclusion, using eCG to increase litter size in goats may be influenced by body weight and breed. MenosABSTRACT.
The incidence of short oestrous cycles and kidding rate in dairy goats were evaluated after administering a low dose (500 IU) of equine chorionic gonadotrophin (eCG) during two breeding seasons. The first year, 46 does (Saanen, n = 10; Nubian, n = 26; and their local crossbred, n = 10) were used. The second year of the study was performed on 34 of the same does (Saanen, n = 4; Nubian, n = 19; local crossbred, n = 11). The goats were synchronised with intravaginal sponges that contained medroxyprogesterone acetate during a period of 14 days. At the time of sponge withdrawal the animals were assigned to two groups: the eCG group was injected with 500 IU of eCG i.m. and the control group was injected with 2 ml of saline solution. Oestrous detection began 12 h after sponge removal. Once a doe was detected to be on heat, it was mated twice: at the moment of detected heat and 12 h later. The animals which presented short cycles were mated again according to the same schedule. To determine the progesterone concentration, all of the animals were bled on the day of standing heat and every second day over a period of 22 days during the second year. All of the does exhibited oestrus within 4 days after sponge removal. The average time (mean ± SD) between sponge withdrawal and standing heat was significantly shorter in the eCG group than in the control group (34.5 h ± 11.9 versus 42.9 h ± 19.6). More animals in the eCG group returned to oestrus than those in the control group ... Presentar Todo |
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Palabras claves : |
ECG; Goat; Oestrous synchronisation; Progesterone. |
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Asunto categoría : |
L53 Fisiología Animal - Reproducción |
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Marc : |
LEADER 03333naa a2200253 a 4500
001 1060712
005 2020-01-29
008 1999 bl uuuu u00u1 u #d
022 $a0921-4488
024 7 $a10.1016/S0921-4488(99)00024-3$2DOI
100 1 $aREGUEIRO, M.
245 $aEffect of medroxyprogesterone acetate and eCG treatment on the reproductive performance of dairy goats.$h[electronic resource]
260 $c1999
500 $aArticle history: Accepted 27 January 1999.
520 $aABSTRACT. The incidence of short oestrous cycles and kidding rate in dairy goats were evaluated after administering a low dose (500 IU) of equine chorionic gonadotrophin (eCG) during two breeding seasons. The first year, 46 does (Saanen, n = 10; Nubian, n = 26; and their local crossbred, n = 10) were used. The second year of the study was performed on 34 of the same does (Saanen, n = 4; Nubian, n = 19; local crossbred, n = 11). The goats were synchronised with intravaginal sponges that contained medroxyprogesterone acetate during a period of 14 days. At the time of sponge withdrawal the animals were assigned to two groups: the eCG group was injected with 500 IU of eCG i.m. and the control group was injected with 2 ml of saline solution. Oestrous detection began 12 h after sponge removal. Once a doe was detected to be on heat, it was mated twice: at the moment of detected heat and 12 h later. The animals which presented short cycles were mated again according to the same schedule. To determine the progesterone concentration, all of the animals were bled on the day of standing heat and every second day over a period of 22 days during the second year. All of the does exhibited oestrus within 4 days after sponge removal. The average time (mean ± SD) between sponge withdrawal and standing heat was significantly shorter in the eCG group than in the control group (34.5 h ± 11.9 versus 42.9 h ± 19.6). More animals in the eCG group returned to oestrus than those in the control group (62.5% versus 15%; p < 0.0001). In the eCG group 77.5% Nubian, 63.6% crossbreed and 14.3% Saanen does returned to oestrus while the corresponding percentages for the control group were 8.7, 10 and 42.9%, respectively. Seventy-six percent (n = 19) of the animals which returned to oestrus in the eCG group did so after a short oestrous cycle, while the corresponding figure in the control group was 16.7% (n = 1) (p = 0.0051). Mean progesterone levels in the mid luteal phase of pregnant and non-pregnant eCG treated animals, were higher than the levels found in the control group. Kidding rates differed significantly between eCG-treated (41.0%) and control animals (64.1%) (p < 0.05), but no significant difference was observed in the mean number of live kids born per doe. Animals weighing less had a higher incidence of short oestrous cycles and a lower kidding rate than heavier animals. In conclusion, using eCG to increase litter size in goats may be influenced by body weight and breed.
653 $aECG
653 $aGoat
653 $aOestrous synchronisation
653 $aProgesterone
700 1 $aPÉREZ-CLARIGET, R.
700 1 $aGANZÁBAL, A.
700 1 $aABA, M.
700 1 $aFORSBERG, M.
773 $tSmall Ruminant Research, August 1999, Volume 33, Issue 3, Pages 223-230. Doi: https://doi.org/10.1016/S0921-4488(99)00024-3
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha actual : |
05/12/2016 |
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Actualizado : |
09/10/2019 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
VERDES, J. M.; MÁRQUEZ, M.; CALLIARI, A.; BATES, D.; MORAÑA, J. A.; GIMENO, E. J.; ODRIOZOLA, E.; GIANNITTI, F.; GUERRERO, F.; FIDALGO, L. E.; PUMAROLA, M. |
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Afiliación : |
JOSÉ MANUEL VERDES, Universidad de la República (UdelaR)/ Facultad de Veterinaria; MEC/ IIBCE (Instituto de Investigaciones de Ciencias Biológicas "Clemente Estable"); MERCEDES MÁRQUEZ, Universidad de Santiago de Compostela (USC); ALDO CALLIARI, Universidad de la República (UdelaR)/ Facultad de Veterinaria; MEC/ IIBCE (Instituto de Investigaciones de Ciencias Biológicas "Clemente Estable"); DANIEL BATES, Universidad de la República (UdelaR)/ Facultad de Veterinaria; JOSÉ ANTONIO MORAÑA, Universidad de la República (UdelaR)/ Facultad de Veterinaria; EDUARDO JUAN GIMENO, Universidad Nacional de la Plata (UNLP); ERNESTO ODRIOZOLA, INTA (Instituto Nacional de Tecnología Agropecuaria)- Balcarce; FEDERICO GIANNITTI, University of Minnesota, Saint Paul, MN, USA; INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FLORENTINA GUERRERO, Universidad de Santiago de Compostela (USC); LUIS EUSEBIO FIDALGO, Universidad de Santiago de Compostela (USC); MARTÍ PUMAROLA, Universitat Autònoma de Barcelona. |
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Título : |
A novel pathogenic mechanism for cerebellar lesions produced by Solanum bonariense in cattle. (Full Scientific Report) |
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Fecha de publicación : |
2015 |
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Fuente / Imprenta : |
Journal of Veterinary Diagnostic Investigation, 2015, v.27 (3): 278-286. |
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DOI : |
10.1177/1040638715582048 |
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Idioma : |
Inglés |
|
Notas : |
Article history: First Published April 21, 2015. |
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Contenido : |
ABSTRACT.
Intoxication with Solanum bonariense in cattle causes cerebellar cortical degeneration with perikaryal vacuolation, axonal swelling, and death primarily of Purkinje cells, with accumulation of electron-dense residual storage bodies in membrane-bound vesicles. The pathogenesis of this disease is not fully understood. Previously, we proposed that inhibition of protein synthesis in Purkinje cells among other altered metabolic pathways could lead to cytoskeletal alterations, subsequently altering cell-specific axonal transport. In the present study, immunohistochemical and histochemical methods were used to identify neuronal cytoskeletal alterations and axonal loss, demyelination, and astrogliosis in the cerebellum of intoxicated bovines. Samples of cerebellum from 3 natural and 4 experimental cases and 2 control bovines were studied. Immunoreactivity against neurofilament (NF)-200KDa confirmed marked loss of Purkinje neurons, and phospho-NF protein, ?-tubulin, and affinity reaction against phalloidin revealed an altered perikaryal distribution of neuronal cytoskeletal proteins in the remaining Purkinje cells in intoxicated cattle. Reactive astrogliosis in every layer of the cerebellar cortex was also observed with anti?glial fibrillary acidic protein immunohistochemistry. In affected cattle, demyelination and axonal loss in the cerebellar white matter, as well as basket cell loss were demonstrated with Klüver?Barrera and Bielschowsky stains, respectively. Based on these results, we propose that neuronal cytoskeletal alterations with subsequent interference of the axonal transport in Purkinje cells may play a relevant role in the pathogenesis of this neurodegenerative disorder, and also that demyelination and axonal loss in the cerebellar white matter, as well as astrogliosis in the gray matter, likely occur secondarily to Purkinje cell degeneration and death.
© 2015 The Author(s). MenosABSTRACT.
Intoxication with Solanum bonariense in cattle causes cerebellar cortical degeneration with perikaryal vacuolation, axonal swelling, and death primarily of Purkinje cells, with accumulation of electron-dense residual storage bodies in membrane-bound vesicles. The pathogenesis of this disease is not fully understood. Previously, we proposed that inhibition of protein synthesis in Purkinje cells among other altered metabolic pathways could lead to cytoskeletal alterations, subsequently altering cell-specific axonal transport. In the present study, immunohistochemical and histochemical methods were used to identify neuronal cytoskeletal alterations and axonal loss, demyelination, and astrogliosis in the cerebellum of intoxicated bovines. Samples of cerebellum from 3 natural and 4 experimental cases and 2 control bovines were studied. Immunoreactivity against neurofilament (NF)-200KDa confirmed marked loss of Purkinje neurons, and phospho-NF protein, ?-tubulin, and affinity reaction against phalloidin revealed an altered perikaryal distribution of neuronal cytoskeletal proteins in the remaining Purkinje cells in intoxicated cattle. Reactive astrogliosis in every layer of the cerebellar cortex was also observed with anti?glial fibrillary acidic protein immunohistochemistry. In affected cattle, demyelination and axonal loss in the cerebellar white matter, as well as basket cell loss were demonstrated with Klüver?Barrera and Bielschowsky stains, respectively. Based on th... Presentar Todo |
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Palabras claves : |
BOVINE; CEREBELLAR DEGENERATION; CYTOSKELETAL DYSFUNCTION; PURKINJE CELLS; SOLANUM BONARIENSE. |
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Thesagro : |
BOVINOS. |
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Asunto categoría : |
L01 Ganadería |
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Marc : |
LEADER 02961naa a2200337 a 4500
001 1056202
005 2019-10-09
008 2015 bl uuuu u00u1 u #d
024 7 $a10.1177/1040638715582048$2DOI
100 1 $aVERDES, J. M.
245 $aA novel pathogenic mechanism for cerebellar lesions produced by Solanum bonariense in cattle. (Full Scientific Report)$h[electronic resource]
260 $c2015
500 $aArticle history: First Published April 21, 2015.
520 $aABSTRACT. Intoxication with Solanum bonariense in cattle causes cerebellar cortical degeneration with perikaryal vacuolation, axonal swelling, and death primarily of Purkinje cells, with accumulation of electron-dense residual storage bodies in membrane-bound vesicles. The pathogenesis of this disease is not fully understood. Previously, we proposed that inhibition of protein synthesis in Purkinje cells among other altered metabolic pathways could lead to cytoskeletal alterations, subsequently altering cell-specific axonal transport. In the present study, immunohistochemical and histochemical methods were used to identify neuronal cytoskeletal alterations and axonal loss, demyelination, and astrogliosis in the cerebellum of intoxicated bovines. Samples of cerebellum from 3 natural and 4 experimental cases and 2 control bovines were studied. Immunoreactivity against neurofilament (NF)-200KDa confirmed marked loss of Purkinje neurons, and phospho-NF protein, ?-tubulin, and affinity reaction against phalloidin revealed an altered perikaryal distribution of neuronal cytoskeletal proteins in the remaining Purkinje cells in intoxicated cattle. Reactive astrogliosis in every layer of the cerebellar cortex was also observed with anti?glial fibrillary acidic protein immunohistochemistry. In affected cattle, demyelination and axonal loss in the cerebellar white matter, as well as basket cell loss were demonstrated with Klüver?Barrera and Bielschowsky stains, respectively. Based on these results, we propose that neuronal cytoskeletal alterations with subsequent interference of the axonal transport in Purkinje cells may play a relevant role in the pathogenesis of this neurodegenerative disorder, and also that demyelination and axonal loss in the cerebellar white matter, as well as astrogliosis in the gray matter, likely occur secondarily to Purkinje cell degeneration and death. © 2015 The Author(s).
650 $aBOVINOS
653 $aBOVINE
653 $aCEREBELLAR DEGENERATION
653 $aCYTOSKELETAL DYSFUNCTION
653 $aPURKINJE CELLS
653 $aSOLANUM BONARIENSE
700 1 $aMÁRQUEZ, M.
700 1 $aCALLIARI, A.
700 1 $aBATES, D.
700 1 $aMORAÑA, J. A.
700 1 $aGIMENO, E. J.
700 1 $aODRIOZOLA, E.
700 1 $aGIANNITTI, F.
700 1 $aGUERRERO, F.
700 1 $aFIDALGO, L. E.
700 1 $aPUMAROLA, M.
773 $tJournal of Veterinary Diagnostic Investigation, 2015$gv.27 (3): 278-286.
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